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SMILES: CCCc1c(C)sc2nc([nH]c(=O)c12)-c1cccc(O)c1O

InChI Key: InChIKey=FJLAWMZPPORSQB-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492103   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50492103
PNG
(CHEMBL2397406)
Show SMILES CCCc1c(C)sc2nc([nH]c(=O)c12)-c1cccc(O)c1O
Show InChI InChI=1S/C16H16N2O3S/c1-3-5-9-8(2)22-16-12(9)15(21)17-14(18-16)10-6-4-7-11(19)13(10)20/h4,6-7,19-20H,3,5H2,1-2H3,(H,17,18,21)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...

J Med Chem 56: 5436-45 (2013)


Article DOI: 10.1021/jm400405z
BindingDB Entry DOI: 10.7270/Q2B27Z7S
More data for this
Ligand-Target Pair