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SMILES: CCCc1c(CC)sc2nc([nH]c(=O)c12)-c1ccc(O)c(O)c1

InChI Key: InChIKey=HXAFMSQRYGOLLR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492106   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50492106
PNG
(CHEMBL2397401)
Show SMILES CCCc1c(CC)sc2nc([nH]c(=O)c12)-c1ccc(O)c(O)c1
Show InChI InChI=1S/C17H18N2O3S/c1-3-5-10-13(4-2)23-17-14(10)16(22)18-15(19-17)9-6-7-11(20)12(21)8-9/h6-8,20-21H,3-5H2,1-2H3,(H,18,19,22)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 590n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...

J Med Chem 56: 5436-45 (2013)


Article DOI: 10.1021/jm400405z
BindingDB Entry DOI: 10.7270/Q2B27Z7S
More data for this
Ligand-Target Pair