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SMILES: COc1ccc(cc1)-c1nc2sc(C)c(C)c2c(=O)[nH]1

InChI Key: InChIKey=GLRQRYIXJVTVQV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492116   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50492116
PNG
(CHEMBL1673237)
Show SMILES COc1ccc(cc1)-c1nc2sc(C)c(C)c2c(=O)[nH]1
Show InChI InChI=1S/C15H14N2O2S/c1-8-9(2)20-15-12(8)14(18)16-13(17-15)10-4-6-11(19-3)7-5-10/h4-7H,1-3H3,(H,16,17,18)
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MMDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.10E+3n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...

J Med Chem 56: 5436-45 (2013)


Article DOI: 10.1021/jm400405z
BindingDB Entry DOI: 10.7270/Q2B27Z7S
More data for this
Ligand-Target Pair