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SMILES: Cc1sc2nc([nH]c(=O)c2c1C)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=PHEQMMMPNJPDAD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492117   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50492117
PNG
(CHEMBL2397278)
Show SMILES Cc1sc2nc([nH]c(=O)c2c1C)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C15H11F3N2OS/c1-7-8(2)22-14-11(7)13(21)19-12(20-14)9-3-5-10(6-4-9)15(16,17)18/h3-6H,1-2H3,(H,19,20,21)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.30E+3n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...

J Med Chem 56: 5436-45 (2013)


Article DOI: 10.1021/jm400405z
BindingDB Entry DOI: 10.7270/Q2B27Z7S
More data for this
Ligand-Target Pair