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SMILES: COc1ccc(cc1OC)-c1nc2sc(C)c(C)c2c(=O)[nH]1

InChI Key: InChIKey=IXNIDWAELHBKKR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492130   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50492130
PNG
(CHEMBL2397288)
Show SMILES COc1ccc(cc1OC)-c1nc2sc(C)c(C)c2c(=O)[nH]1
Show InChI InChI=1S/C16H16N2O3S/c1-8-9(2)22-16-13(8)15(19)17-14(18-16)10-5-6-11(20-3)12(7-10)21-4/h5-7H,1-4H3,(H,17,18,19)
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UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.26E+4n/an/an/an/an/an/a



National Cancer Institute

Curated by ChEMBL


Assay Description
Inhibition of RNase H activity of wild type HIV-1 reverse transcriptase using 18 nucleotide 3'-fluorescein-labeled RNA/18 nucleotide 5'-dabsyl-labele...

J Med Chem 56: 5436-45 (2013)


Article DOI: 10.1021/jm400405z
BindingDB Entry DOI: 10.7270/Q2B27Z7S
More data for this
Ligand-Target Pair