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SMILES: [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2

InChI Key: InChIKey=HIRAHSKWRNEADM-SNVBAGLBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50492240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50492240 (CHEMBL2397908) Show SMILES [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2 |r| Show InChI InChI=1S/C14H18N2O2/c1-2-18-13-5-3-4-11-12(13)8-10-9-15-6-7-16(10)14(11)17/h3-5,10,15H,2,6-9H2,1H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5-HT2C receptor expressed in HEK293E cells after 45 mins by Top counting analysis				Bioorg Med Chem Lett 23: 3914-9 (2013) Article DOI: 10.1016/j.bmcl.2013.04.061 BindingDB Entry DOI: 10.7270/Q2T156KD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50492240 (CHEMBL2397908) Show SMILES [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2 |r| Show InChI InChI=1S/C14H18N2O2/c1-2-18-13-5-3-4-11-12(13)8-10-9-15-6-7-16(10)14(11)17/h3-5,10,15H,2,6-9H2,1H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]LSD from human recombinant 5-HT2B receptor expressed in HEK293E cells after 45 mins by Top counting analysis				Bioorg Med Chem Lett 23: 3914-9 (2013) Article DOI: 10.1016/j.bmcl.2013.04.061 BindingDB Entry DOI: 10.7270/Q2T156KD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50492240 (CHEMBL2397908) Show SMILES [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2 |r| Show InChI InChI=1S/C14H18N2O2/c1-2-18-13-5-3-4-11-12(13)8-10-9-15-6-7-16(10)14(11)17/h3-5,10,15H,2,6-9H2,1H3/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]DOI from human recombinant 5-HT2A receptor expressed in HEK293E cells after 45 mins by Top counting analysis				Bioorg Med Chem Lett 23: 3914-9 (2013) Article DOI: 10.1016/j.bmcl.2013.04.061 BindingDB Entry DOI: 10.7270/Q2T156KD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50492240 (CHEMBL2397908) Show SMILES [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2 |r| Show InChI InChI=1S/C14H18N2O2/c1-2-18-13-5-3-4-11-12(13)8-10-9-15-6-7-16(10)14(11)17/h3-5,10,15H,2,6-9H2,1H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2B receptor expressed in HEK293E cells assessed as increase in intracellular calcium level by FLIPR assay				Bioorg Med Chem Lett 23: 3914-9 (2013) Article DOI: 10.1016/j.bmcl.2013.04.061 BindingDB Entry DOI: 10.7270/Q2T156KD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50492240 (CHEMBL2397908) Show SMILES [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2 |r| Show InChI InChI=1S/C14H18N2O2/c1-2-18-13-5-3-4-11-12(13)8-10-9-15-6-7-16(10)14(11)17/h3-5,10,15H,2,6-9H2,1H3/t10-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2A receptor expressed in HEK293E cells assessed as increase in intracellular calcium level by FLIPR assay				Bioorg Med Chem Lett 23: 3914-9 (2013) Article DOI: 10.1016/j.bmcl.2013.04.061 BindingDB Entry DOI: 10.7270/Q2T156KD
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50492240 (CHEMBL2397908) Show SMILES [H][C@@]12CNCCN1C(=O)c1cccc(OCC)c1C2 |r| Show InChI InChI=1S/C14H18N2O2/c1-2-18-13-5-3-4-11-12(13)8-10-9-15-6-7-16(10)14(11)17/h3-5,10,15H,2,6-9H2,1H3/t10-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5-HT2C receptor expressed in HEK293E cells assessed as increase in intracellular calcium level by FLIPR assay				Bioorg Med Chem Lett 23: 3914-9 (2013) Article DOI: 10.1016/j.bmcl.2013.04.061 BindingDB Entry DOI: 10.7270/Q2T156KD
					More data for this Ligand-Target Pair