BDBM50492330 CHEMBL2402960

SMILES: Cc1cc(Oc2ccc(OCc3ccccc3)cc2)nc(Nc2ccc(cc2)C#N)n1

InChI Key: InChIKey=MMTAITRQZNGREO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50492330 (CHEMBL2402960) Show SMILES Cc1cc(Oc2ccc(OCc3ccccc3)cc2)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C25H20N4O2/c1-18-15-24(29-25(27-18)28-21-9-7-19(16-26)8-10-21)31-23-13-11-22(12-14-23)30-17-20-5-3-2-4-6-20/h2-15H,17H2,1H3,(H,27,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type HIV1 RT using poly(rA)/oligo(dT)16 as template after 40 mins by spectrofluorometric analysis				Eur J Med Chem 65: 134-43 (2013) Article DOI: 10.1016/j.ejmech.2013.04.052 BindingDB Entry DOI: 10.7270/Q2736TTS
					More data for this Ligand-Target Pair