BDBM50492331 CHEMBL2402959

SMILES: Cc1cc(Oc2ccc(cc2)C(=O)c2ccc(O)cc2)nc(Nc2ccc(cc2)C#N)n1

InChI Key: InChIKey=IOPOMWMEFVLLHU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492331   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50492331 (CHEMBL2402959) Show SMILES Cc1cc(Oc2ccc(cc2)C(=O)c2ccc(O)cc2)nc(Nc2ccc(cc2)C#N)n1 Show InChI InChI=1S/C25H18N4O3/c1-16-14-23(29-25(27-16)28-20-8-2-17(15-26)3-9-20)32-22-12-6-19(7-13-22)24(31)18-4-10-21(30)11-5-18/h2-14,30H,1H3,(H,27,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type HIV1 RT using poly(rA)/oligo(dT)16 as template after 40 mins by spectrofluorometric analysis				Eur J Med Chem 65: 134-43 (2013) Article DOI: 10.1016/j.ejmech.2013.04.052 BindingDB Entry DOI: 10.7270/Q2736TTS
					More data for this Ligand-Target Pair