BDBM50492334 CHEMBL2402963

SMILES: Cc1cc(C)cc(c1)C(=O)c1cc(Cl)ccc1Oc1nc(Nc2ccc(cc2)C#N)ncc1C

InChI Key: InChIKey=GLWGRMNRPAAQMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50492334 (CHEMBL2402963) Show SMILES Cc1cc(C)cc(c1)C(=O)c1cc(Cl)ccc1Oc1nc(Nc2ccc(cc2)C#N)ncc1C Show InChI InChI=1S/C27H21ClN4O2/c1-16-10-17(2)12-20(11-16)25(33)23-13-21(28)6-9-24(23)34-26-18(3)15-30-27(32-26)31-22-7-4-19(14-29)5-8-22/h4-13,15H,1-3H3,(H,30,31,32)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fudan University Curated by ChEMBL					Assay Description Inhibition of recombinant wild type HIV1 RT using poly(rA)/oligo(dT)16 as template after 40 mins by spectrofluorometric analysis				Eur J Med Chem 65: 134-43 (2013) Article DOI: 10.1016/j.ejmech.2013.04.052 BindingDB Entry DOI: 10.7270/Q2736TTS
					More data for this Ligand-Target Pair