BDBM50492407 CHEMBL2403449

SMILES: COc1cccc2sc(cc12)C(=O)NO

InChI Key: InChIKey=HDSAWWRRSVJRDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492407   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50492407 (CHEMBL2403449) Show SMILES COc1cccc2sc(cc12)C(=O)NO Show InChI InChI=1S/C10H9NO3S/c1-14-7-3-2-4-8-6(7)5-9(15-8)10(12)11-13/h2-5,13H,1H3,(H,11,12)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Menarini Ricerche Curated by ChEMBL					Assay Description Inhibition of HDAC in human HeLa cells assessed as deacetylation of substrate by fluorescence plate reader analysis				Bioorg Med Chem Lett 23: 4091-5 (2013) Article DOI: 10.1016/j.bmcl.2013.05.053 BindingDB Entry DOI: 10.7270/Q22F7RCD
					More data for this Ligand-Target Pair