BDBM50492704 CHEMBL2408152
SMILES: Clc1ccc(NC(=O)c2cc3CCCCn3n2)nc1
InChI Key: InChIKey=WDRXDJHWZLRTMQ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor (Rattus norvegicus (Rat)) | BDBM50492704![]() (CHEMBL2408152) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 262 | n/a | n/a | n/a | n/a | n/a | n/a |
Addex Therapeutics Curated by ChEMBL | Assay Description Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass... | Bioorg Med Chem Lett 23: 4523-7 (2013) Article DOI: 10.1016/j.bmcl.2013.06.044 BindingDB Entry DOI: 10.7270/Q29S1V02 | |||||||||||
More data for this Ligand-Target Pair |