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SMILES: N#Cc1ccc(COc2cc3CCCCn3n2)nc1

InChI Key: InChIKey=VRLYYUCAOLPBEH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492721   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50492721
PNG
(CHEMBL2408183)
Show SMILES N#Cc1ccc(COc2cc3CCCCn3n2)nc1
Show InChI InChI=1S/C14H14N4O/c15-8-11-4-5-12(16-9-11)10-19-14-7-13-3-1-2-6-18(13)17-14/h4-5,7,9H,1-3,6,10H2
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n/an/a 316n/an/an/an/an/an/a



Addex Therapeutics

Curated by ChEMBL


Assay Description
Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...

Bioorg Med Chem Lett 23: 4523-7 (2013)


Article DOI: 10.1016/j.bmcl.2013.06.044
BindingDB Entry DOI: 10.7270/Q29S1V02
More data for this
Ligand-Target Pair