BDBM50492726 CHEMBL2408161

SMILES: Clc1c2CCCCn2nc1C(=O)Cc1ccc(cn1)C#N

InChI Key: InChIKey=ZSXQLCPBAMUAJS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492726   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (Rattus norvegicus (Rat))	BDBM50492726 (CHEMBL2408161) Show SMILES Clc1c2CCCCn2nc1C(=O)Cc1ccc(cn1)C#N Show InChI InChI=1S/C15H13ClN4O/c16-14-12-3-1-2-6-20(12)19-15(14)13(21)7-11-5-4-10(8-17)9-18-11/h4-5,9H,1-3,6-7H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
Addex Therapeutics Curated by ChEMBL					Assay Description Negative allosteric modulation of rat mGluR5 receptor expressed in HEK293 cells assessed as intracellular calcium flux after 170 seconds by FLIPR ass...				Bioorg Med Chem Lett 23: 4523-7 (2013) Article DOI: 10.1016/j.bmcl.2013.06.044 BindingDB Entry DOI: 10.7270/Q29S1V02
					More data for this Ligand-Target Pair