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SMILES: Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1

InChI Key: InChIKey=UMGYDBQRRRBPHS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50492801   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from 5HT1A receptor in rat brain hippocampal membranes after 15 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 from D2 receptor in rat brain striatal membranes after 60 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (Rattus norvegicus (rat))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	570	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-prozosin from alpha1B adrenoreceptor in rat liver membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-RX821002 from alpha2 adrenoreceptor in rat brain cortical membranes after 45 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-ketanserin from 5HT2A receptor in rat brain cortical membranes after 15 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 from human D4 receptor after 120 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50492801 (CHEMBL2414357) Show SMILES Clc1ccc(cc1)-n1cc(CCCCN2CCN(CC2)c2ccccc2)cn1 Show InChI InChI=1S/C23H27ClN4/c24-21-9-11-23(12-10-21)28-19-20(18-25-28)6-4-5-13-26-14-16-27(17-15-26)22-7-2-1-3-8-22/h1-3,7-12,18-19H,4-6,13-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal do Rio de Janeiro Curated by ChEMBL					Assay Description Displacement of [3H]-mesulergine from human 5HT2C receptor after 60 mins by liquid scintillation counting				Eur J Med Chem 66: 122-34 (2013) Article DOI: 10.1016/j.ejmech.2013.05.027 BindingDB Entry DOI: 10.7270/Q2514253
					More data for this Ligand-Target Pair