BDBM50492898 CHEMBL2414176
SMILES: [#6]-[#7](-[#6]-[#6]\[#6]=[#6](/c1ccccc1)-c1ccccc1)-[#6](-[#6]-[#6]-[#8])-[#6](=O)-[#7]-[#6]-c1ccccc1Cl
InChI Key: InChIKey=MOVIWRDBUGATOV-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium- and chloride-dependent GABA transporter 1 (Rattus norvegicus) | BDBM50492898 (CHEMBL2414176) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of mouse GAT1-mediated [3H]GABA uptake stably transfected in HEK293 cells | Bioorg Med Chem 21: 5154-67 (2013) Article DOI: 10.1016/j.bmc.2013.06.038 BindingDB Entry DOI: 10.7270/Q208688J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA transporter (Mus musculus) | BDBM50492898 (CHEMBL2414176) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of mouse GAT2-mediated [3H]GABA uptake stably transfected in HEK293 cells | Bioorg Med Chem 21: 5154-67 (2013) Article DOI: 10.1016/j.bmc.2013.06.038 BindingDB Entry DOI: 10.7270/Q208688J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
GABA transporter (Mus musculus) | BDBM50492898 (CHEMBL2414176) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Inhibition of mouse GAT3-mediated [3H]GABA uptake stably transfected in HEK293 cells | Bioorg Med Chem 21: 5154-67 (2013) Article DOI: 10.1016/j.bmc.2013.06.038 BindingDB Entry DOI: 10.7270/Q208688J | |||||||||||
More data for this Ligand-Target Pair |