BDBM50493359 CHEMBL2425430
SMILES: OC(=O)C(F)(F)F.CN([C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCCO)C(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1
InChI Key: InChIKey=QQQMZBQLIQMUEY-IUQRHOJWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50493359 (CHEMBL2425430) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 155 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi "G. d'Annunzio" di Chieti-Pescara Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation counting | Eur J Med Chem 68: 167-77 (2013) Article DOI: 10.1016/j.ejmech.2013.07.044 BindingDB Entry DOI: 10.7270/Q2D79FCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50493359 (CHEMBL2425430) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi "G. d'Annunzio" di Chieti-Pescara Curated by ChEMBL | Assay Description Displacement of [3H]Ile5,6deltorphin-2 from delta opioid receptor in Wistar rat brain membranes by liquid scintillation counting | Eur J Med Chem 68: 167-77 (2013) Article DOI: 10.1016/j.ejmech.2013.07.044 BindingDB Entry DOI: 10.7270/Q2D79FCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50493359 (CHEMBL2425430) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+14 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi "G. d'Annunzio" di Chieti-Pescara Curated by ChEMBL | Assay Description Displacement of [3H]DAMGO from mu opioid receptor in Wistar rat brain membranes by liquid scintillation counting | Eur J Med Chem 68: 167-77 (2013) Article DOI: 10.1016/j.ejmech.2013.07.044 BindingDB Entry DOI: 10.7270/Q2D79FCG | |||||||||||
More data for this Ligand-Target Pair |