BDBM50493590 CHEMBL2435830

SMILES: CCCNC(=O)c1cc(C)c2nc(CCC)n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c2c1

InChI Key: InChIKey=MZEZWAFSRHXIMS-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493590   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (Homo sapiens (Human))	BDBM50493590 (CHEMBL2435830) Show SMILES CCCNC(=O)c1cc(C)c2nc(CCC)n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c2c1 Show InChI InChI=1S/C29H31N3O3/c1-4-8-26-31-27-19(3)16-22(28(33)30-15-5-2)17-25(27)32(26)18-20-11-13-21(14-12-20)23-9-6-7-10-24(23)29(34)35/h6-7,9-14,16-17H,4-5,8,15,18H2,1-3H3,(H,30,33)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beijing Institute of Technology Curated by ChEMBL					Assay Description Displacement of [125I]-Sar1Ile8-angiotensin 2 from angiotensin 2 AT1 receptor (unknown origin) after 180 mins by gamma counting analysis				Eur J Med Chem 69: 44-54 (2013) Article DOI: 10.1016/j.ejmech.2013.08.014 BindingDB Entry DOI: 10.7270/Q2PK0K32
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