BDBM50493802 CHEMBL2443272

SMILES: Clc1cccc(CNCC[C@]2(CCOC3(CCCC3)C2)c2ccccn2)c1

InChI Key: InChIKey=WFDROGGCSKQUSJ-JOCHJYFZSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493802   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50493802 (CHEMBL2443272) Show SMILES Clc1cccc(CNCC[C@]2(CCOC3(CCCC3)C2)c2ccccn2)c1 |r| Show InChI InChI=1S/C23H29ClN2O/c24-20-7-5-6-19(16-20)17-25-14-11-22(21-8-1-4-13-26-21)12-15-27-23(18-22)9-2-3-10-23/h1,4-8,13,16,25H,2-3,9-12,14-15,17-18H2/t22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
Trevena, Inc. Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...				J Med Chem 56: 8019-31 (2013) Article DOI: 10.1021/jm4010829 BindingDB Entry DOI: 10.7270/Q2FT8Q0N
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50493802 (CHEMBL2443272) Show SMILES Clc1cccc(CNCC[C@]2(CCOC3(CCCC3)C2)c2ccccn2)c1 |r| Show InChI InChI=1S/C23H29ClN2O/c24-20-7-5-6-19(16-20)17-25-14-11-22(21-8-1-4-13-26-21)12-15-27-23(18-22)9-2-3-10-23/h1,4-8,13,16,25H,2-3,9-12,14-15,17-18H2/t22-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Trevena, Inc. Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assay				J Med Chem 56: 8019-31 (2013) Article DOI: 10.1021/jm4010829 BindingDB Entry DOI: 10.7270/Q2FT8Q0N
					More data for this Ligand-Target Pair