BDBM50493816 CHEMBL2443283

SMILES: CC1(C)CC(CCNCc2ccccc2)(CCO1)c1ccc(F)cc1

InChI Key: InChIKey=CUCKSFZHRXPXND-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50493816 (CHEMBL2443283) Show SMILES CC1(C)CC(CCNCc2ccccc2)(CCO1)c1ccc(F)cc1 Show InChI InChI=1S/C22H28FNO/c1-21(2)17-22(13-15-25-21,19-8-10-20(23)11-9-19)12-14-24-16-18-6-4-3-5-7-18/h3-11,24H,12-17H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a
Trevena, Inc. Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...				J Med Chem 56: 8019-31 (2013) Article DOI: 10.1021/jm4010829 BindingDB Entry DOI: 10.7270/Q2FT8Q0N
					More data for this Ligand-Target Pair