BDBM50493822 CHEMBL2443274

SMILES: C(C[C@]1(CCOC2(CCCC2)C1)c1ccccn1)NCc1cccnc1

InChI Key: InChIKey=BMMVFQHOKOLWTG-OAQYLSRUSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493822   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50493822 (CHEMBL2443274) Show SMILES C(C[C@]1(CCOC2(CCCC2)C1)c1ccccn1)NCc1cccnc1 |r| Show InChI InChI=1S/C22H29N3O/c1-4-13-25-20(7-1)21(10-14-24-17-19-6-5-12-23-16-19)11-15-26-22(18-21)8-2-3-9-22/h1,4-7,12-13,16,24H,2-3,8-11,14-15,17-18H2/t21-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Trevena, Inc. Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...				J Med Chem 56: 8019-31 (2013) Article DOI: 10.1021/jm4010829 BindingDB Entry DOI: 10.7270/Q2FT8Q0N
					More data for this Ligand-Target Pair