BDBM50493825 CHEMBL2443263

SMILES: Fc1ccc(cc1)[C@]1(CCNCc2ccccc2)CCOC2(CCCC2)C1

InChI Key: InChIKey=NBXSEADGQTYSNU-HSZRJFAPSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50493825 (CHEMBL2443263) Show SMILES Fc1ccc(cc1)[C@]1(CCNCc2ccccc2)CCOC2(CCCC2)C1 |r| Show InChI InChI=1S/C24H30FNO/c25-22-10-8-21(9-11-22)23(14-16-26-18-20-6-2-1-3-7-20)15-17-27-24(19-23)12-4-5-13-24/h1-3,6-11,26H,4-5,12-19H2/t23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Trevena, Inc. Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assay				J Med Chem 56: 8019-31 (2013) Article DOI: 10.1021/jm4010829 BindingDB Entry DOI: 10.7270/Q2FT8Q0N
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50493825 (CHEMBL2443263) Show SMILES Fc1ccc(cc1)[C@]1(CCNCc2ccccc2)CCOC2(CCCC2)C1 |r| Show InChI InChI=1S/C24H30FNO/c25-22-10-8-21(9-11-22)23(14-16-26-18-20-6-2-1-3-7-20)15-17-27-24(19-23)12-4-5-13-24/h1-3,6-11,26H,4-5,12-19H2/t23-/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Trevena, Inc. Curated by ChEMBL					Assay Description Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...				J Med Chem 56: 8019-31 (2013) Article DOI: 10.1021/jm4010829 BindingDB Entry DOI: 10.7270/Q2FT8Q0N
					More data for this Ligand-Target Pair