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SMILES: Cl.FC(F)(F)c1ccc(CCCCNC(=N)SCCCN2CCCCC2)cc1

InChI Key: InChIKey=RLQSEYDCCHGXGP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494127   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50494127
PNG
(CHEMBL2441944)
Show SMILES Cl.FC(F)(F)c1ccc(CCCCNC(=N)SCCCN2CCCCC2)cc1
Show InChI InChI=1S/C20H30F3N3S/c21-20(22,23)18-10-8-17(9-11-18)7-2-3-12-25-19(24)27-16-6-15-26-13-4-1-5-14-26/h8-11H,1-7,12-16H2,(H2,24,25)
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PC cid
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Article
PubMed
n/an/a 16n/an/an/an/an/an/a



Osaka University of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in CHO cells assessed as inhibition of forskolin/R-alpha-methylhistamine-induced cAMP ac...

Bioorg Med Chem Lett 23: 6415-20 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.052
BindingDB Entry DOI: 10.7270/Q2R78J5R
More data for this
Ligand-Target Pair