BindingDB logo
myBDB logout

null

SMILES: Cl.Clc1ccc(CCNC(=N)SCCCN2CCCC2)cc1

InChI Key: InChIKey=MEFRYVMTAZKWAB-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494139   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50494139
PNG
(CHEMBL2441938)
Show SMILES Cl.Clc1ccc(CCNC(=N)SCCCN2CCCC2)cc1
Show InChI InChI=1S/C16H24ClN3S/c17-15-6-4-14(5-7-15)8-9-19-16(18)21-13-3-12-20-10-1-2-11-20/h4-7H,1-3,8-13H2,(H2,18,19)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 32n/an/an/an/an/an/a



Osaka University of Pharmaceutical Sciences

Curated by ChEMBL


Assay Description
Antagonist activity at human histamine H3 receptor expressed in CHO cells assessed as inhibition of forskolin/R-alpha-methylhistamine-induced cAMP ac...

Bioorg Med Chem Lett 23: 6415-20 (2013)


Article DOI: 10.1016/j.bmcl.2013.09.052
BindingDB Entry DOI: 10.7270/Q2R78J5R
More data for this
Ligand-Target Pair