null

SMILES: ONC(=O)COCc1ccc(cc1)C#Cc1ccc(CN2CCOCC2)cc1

InChI Key: InChIKey=QFKDCGAKZLTRIH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50495312 (CHEMBL3103550) Show SMILES ONC(=O)COCc1ccc(cc1)C#Cc1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C22H24N2O4/c25-22(23-26)17-28-16-21-9-5-19(6-10-21)2-1-18-3-7-20(8-4-18)15-24-11-13-27-14-12-24/h3-10,26H,11-17H2,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Westf£lischen Wilhelms-Universit£t M£nster Curated by ChEMBL					Assay Description Inhibition of Escherichia coli LpxC using UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine as substrate incubated for 30 mins prior to enzyme add...				Bioorg Med Chem 22: 1016-28 (2014) Article DOI: 10.1016/j.bmc.2013.12.057 BindingDB Entry DOI: 10.7270/Q2X92F7C
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Escherichia coli)	BDBM50495312 (CHEMBL3103550) Show SMILES ONC(=O)COCc1ccc(cc1)C#Cc1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C22H24N2O4/c25-22(23-26)17-28-16-21-9-5-19(6-10-21)2-1-18-3-7-20(8-4-18)15-24-11-13-27-14-12-24/h3-10,26H,11-17H2,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut f£r Pharmazeutische und Medizinische Chemie der Westf£lischen Wilhelms-Universit£t M£nster Curated by ChEMBL					Assay Description Inhibition of Escherichia coli LpxC using UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine as substrate incubated for 30 mins prior to enzyme add...				Bioorg Med Chem 22: 1016-28 (2014) Article DOI: 10.1016/j.bmc.2013.12.057 BindingDB Entry DOI: 10.7270/Q2X92F7C
					More data for this Ligand-Target Pair