BDBM50495430 CHEMBL3108803

SMILES: Cc1nnc2c3ccccc3c(nn12)-c1ccc(N2CCOCC2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1

InChI Key: InChIKey=RHPSSUMJYGAMNR-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50495430   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 9 (Homo sapiens (Human))	BDBM50495430 (CHEMBL3108803) Show SMILES Cc1nnc2c3ccccc3c(nn12)-c1ccc(N2CCOCC2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H23ClN6O3S/c1-17-28-29-26-22-5-3-2-4-21(22)25(30-33(17)26)18-6-11-24(32-12-14-36-15-13-32)23(16-18)31-37(34,35)20-9-7-19(27)8-10-20/h2-11,16,31H,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H2K9(Ac)K13(Ac)K15(Ac) peptide from BRD9 bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
Cat eye syndrome critical region protein 2 (Homo sapiens (Human))	BDBM50495430 (CHEMBL3108803) Show SMILES Cc1nnc2c3ccccc3c(nn12)-c1ccc(N2CCOCC2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H23ClN6O3S/c1-17-28-29-26-22-5-3-2-4-21(22)25(30-33(17)26)18-6-11-24(32-12-14-36-15-13-32)23(16-18)31-37(34,35)20-9-7-19(27)8-10-20/h2-11,16,31H,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H4Ac4 peptide from CECR2 bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50495430 (CHEMBL3108803) Show SMILES Cc1nnc2c3ccccc3c(nn12)-c1ccc(N2CCOCC2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H23ClN6O3S/c1-17-28-29-26-22-5-3-2-4-21(22)25(30-33(17)26)18-6-11-24(32-12-14-36-15-13-32)23(16-18)31-37(34,35)20-9-7-19(27)8-10-20/h2-11,16,31H,12-15H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H4Ac4 peptide from BRD4 bromodomain-1 (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM50495430 (CHEMBL3108803) Show SMILES Cc1nnc2c3ccccc3c(nn12)-c1ccc(N2CCOCC2)c(NS(=O)(=O)c2ccc(Cl)cc2)c1 Show InChI InChI=1S/C26H23ClN6O3S/c1-17-28-29-26-22-5-3-2-4-21(22)25(30-33(17)26)18-6-11-24(32-12-14-36-15-13-32)23(16-18)31-37(34,35)20-9-7-19(27)8-10-20/h2-11,16,31H,12-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H3K56(Ac) peptide from CREBBP bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair