BDBM50495432 CHEMBL3108806

SMILES: CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12

InChI Key: InChIKey=PMYGONIFXBXQCE-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50495432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cat eye syndrome critical region protein 2 (Homo sapiens (Human))	BDBM50495432 (CHEMBL3108806) Show SMILES CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12 Show InChI InChI=1S/C20H19N5O/c1-4-18(26)21-17-11-14(10-9-12(17)2)19-15-7-5-6-8-16(15)20-23-22-13(3)25(20)24-19/h5-11H,4H2,1-3H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H4Ac4 peptide from CECR2 bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
Transcription intermediary factor 1-alpha (Homo sapiens (Human))	BDBM50495432 (CHEMBL3108806) Show SMILES CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12 Show InChI InChI=1S/C20H19N5O/c1-4-18(26)21-17-11-14(10-9-12(17)2)19-15-7-5-6-8-16(15)20-23-22-13(3)25(20)24-19/h5-11H,4H2,1-3H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H3K14(Ac) peptide from TIF1alpha bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
Bromodomain adjacent to zinc finger domain protein 2B (Homo sapiens (Human))	BDBM50495432 (CHEMBL3108806) Show SMILES CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12 Show InChI InChI=1S/C20H19N5O/c1-4-18(26)21-17-11-14(10-9-12(17)2)19-15-7-5-6-8-16(15)20-23-22-13(3)25(20)24-19/h5-11H,4H2,1-3H3,(H,21,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H3K14(Ac) peptide from BAZ2B bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50495432 (CHEMBL3108806) Show SMILES CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12 Show InChI InChI=1S/C20H19N5O/c1-4-18(26)21-17-11-14(10-9-12(17)2)19-15-7-5-6-8-16(15)20-23-22-13(3)25(20)24-19/h5-11H,4H2,1-3H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H4Ac4 peptide from BRD4 bromodomain-1 (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
Protein polybromo-1 (Homo sapiens (Human))	BDBM50495432 (CHEMBL3108806) Show SMILES CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12 Show InChI InChI=1S/C20H19N5O/c1-4-18(26)21-17-11-14(10-9-12(17)2)19-15-7-5-6-8-16(15)20-23-22-13(3)25(20)24-19/h5-11H,4H2,1-3H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H3K14(Ac) peptide from PB1-5 bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM50495432 (CHEMBL3108806) Show SMILES CCC(=O)Nc1cc(ccc1C)-c1nn2c(C)nnc2c2ccccc12 Show InChI InChI=1S/C20H19N5O/c1-4-18(26)21-17-11-14(10-9-12(17)2)19-15-7-5-6-8-16(15)20-23-22-13(3)25(20)24-19/h5-11H,4H2,1-3H3,(H,21,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Displacement of H3K56(Ac) peptide from CREBBP bromodomain (unknown origin) by AlphaScreen assay				J Med Chem 57: 462-76 (2014) Article DOI: 10.1021/jm401568s BindingDB Entry DOI: 10.7270/Q2CC13PD
					More data for this Ligand-Target Pair