BDBM50495476 CHEMBL3109078

SMILES: OC(=O)[C@H]1[C@@H](Cc2c[nH]c3ccccc23)CCN1C(=O)c1ccccc1

InChI Key: InChIKey=SFTGLDWKERDMBL-DNVCBOLYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495476   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM50495476 (CHEMBL3109078) Show SMILES OC(=O)[C@H]1[C@@H](Cc2c[nH]c3ccccc23)CCN1C(=O)c1ccccc1 |r| Show InChI InChI=1S/C21H20N2O3/c24-20(14-6-2-1-3-7-14)23-11-10-15(19(23)21(25)26)12-16-13-22-18-9-5-4-8-17(16)18/h1-9,13,15,19,22H,10-12H2,(H,25,26)/t15-,19-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Pierre et Marie Curie-Paris 6 Curated by ChEMBL					Assay Description Inhibition of human recombinant DNMT1 expressed in H19 cells assessed as inhibition of tritiated methyl incorporation from [3H]-labeled AdoMet into h...				J Med Chem 57: 421-34 (2014) Article DOI: 10.1021/jm401419p BindingDB Entry DOI: 10.7270/Q2QN69Q3
					More data for this Ligand-Target Pair