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SMILES: Oc1cccc(c1)-c1nc(nc2cccnc12)N1CCOCC1

InChI Key: InChIKey=YVLVIUASDJALDE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495497   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495497 (CHEMBL3109115) Show SMILES Oc1cccc(c1)-c1nc(nc2cccnc12)N1CCOCC1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)15-16-14(5-2-6-18-16)19-17(20-15)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	453	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495497 (CHEMBL3109115) Show SMILES Oc1cccc(c1)-c1nc(nc2cccnc12)N1CCOCC1 Show InChI InChI=1S/C17H16N4O2/c22-13-4-1-3-12(11-13)15-16-14(5-2-6-18-16)19-17(20-15)21-7-9-23-10-8-21/h1-6,11,22H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair