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SMILES: Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1

InChI Key: InChIKey=MCDDZMMDVXAFRK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50495501   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of mTOR (unknown origin) after 2 hrs by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50495501 (CHEMBL3109133) Show SMILES Nc1ccc(cn1)-c1nc(N2CCOCC2)c2ncccc2n1 Show InChI InChI=1S/C16H16N6O/c17-13-4-3-11(10-19-13)15-20-12-2-1-5-18-14(12)16(21-15)22-6-8-23-9-7-22/h1-5,10H,6-9H2,(H2,17,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ d'Orl£ans Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) after 1 hr by TR-FRET assay				J Med Chem 57: 613-31 (2014) Article DOI: 10.1021/jm401138v BindingDB Entry DOI: 10.7270/Q2G44T8C
					More data for this Ligand-Target Pair