null

SMILES: OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc3ccccc3c2)cc1

InChI Key: InChIKey=KWVNFINHBUVENO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50495760 (CHEMBL3114941) Show SMILES OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C25H21N3O4S/c29-22(30)14-16-7-11-20(12-8-16)26-25-23-21(6-3-13-33(23,31)32)27-24(28-25)19-10-9-17-4-1-2-5-18(17)15-19/h1-2,4-5,7-12,15H,3,6,13-14H2,(H,29,30)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50495760 (CHEMBL3114941) Show SMILES OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc3ccccc3c2)cc1 Show InChI InChI=1S/C25H21N3O4S/c29-22(30)14-16-7-11-20(12-8-16)26-25-23-21(6-3-13-33(23,31)32)27-24(28-25)19-10-9-17-4-1-2-5-18(17)15-19/h1-2,4-5,7-12,15H,3,6,13-14H2,(H,29,30)(H,26,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair