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SMILES: CN(C)c1ccc(cn1)-c1nc2CCCSc2c(Nc2ccc(CC(O)=O)cc2)n1

InChI Key: InChIKey=IZADTQKIASBMJF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495768   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50495768 (CHEMBL3114931) Show SMILES CN(C)c1ccc(cn1)-c1nc2CCCSc2c(Nc2ccc(CC(O)=O)cc2)n1 Show InChI InChI=1S/C22H23N5O2S/c1-27(2)18-10-7-15(13-23-18)21-25-17-4-3-11-30-20(17)22(26-21)24-16-8-5-14(6-9-16)12-19(28)29/h5-10,13H,3-4,11-12H2,1-2H3,(H,28,29)(H,24,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50495768 (CHEMBL3114931) Show SMILES CN(C)c1ccc(cn1)-c1nc2CCCSc2c(Nc2ccc(CC(O)=O)cc2)n1 Show InChI InChI=1S/C22H23N5O2S/c1-27(2)18-10-7-15(13-23-18)21-25-17-4-3-11-30-20(17)22(26-21)24-16-8-5-14(6-9-16)12-19(28)29/h5-10,13H,3-4,11-12H2,1-2H3,(H,28,29)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair