null

SMILES: OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc(cc2)-c2ccccc2)cc1

InChI Key: InChIKey=FXWZTQOSDZFWIN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495783   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50495783 (CHEMBL3114942) Show SMILES OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H23N3O4S/c31-24(32)17-18-8-14-22(15-9-18)28-27-25-23(7-4-16-35(25,33)34)29-26(30-27)21-12-10-20(11-13-21)19-5-2-1-3-6-19/h1-3,5-6,8-15H,4,7,16-17H2,(H,31,32)(H,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50495783 (CHEMBL3114942) Show SMILES OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H23N3O4S/c31-24(32)17-18-8-14-22(15-9-18)28-27-25-23(7-4-16-35(25,33)34)29-26(30-27)21-12-10-20(11-13-21)19-5-2-1-3-6-19/h1-3,5-6,8-15H,4,7,16-17H2,(H,31,32)(H,28,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4D2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair