BDBM50496070 CHEMBL3120987

SMILES: Cn1c(nc(c1-c1ccncc1)-c1ccc(F)cc1)-c1cn(nn1)-c1cccc(c1)C(=O)NCCCO

InChI Key: InChIKey=WWSNBGWXZWKDMF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496070   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50496070 (CHEMBL3120987) Show SMILES Cn1c(nc(c1-c1ccncc1)-c1ccc(F)cc1)-c1cn(nn1)-c1cccc(c1)C(=O)NCCCO Show InChI InChI=1S/C27H24FN7O2/c1-34-25(19-10-13-29-14-11-19)24(18-6-8-21(28)9-7-18)31-26(34)23-17-35(33-32-23)22-5-2-4-20(16-22)27(37)30-12-3-15-36/h2,4-11,13-14,16-17,36H,3,12,15H2,1H3,(H,30,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Syncom B.V. Curated by ChEMBL					Assay Description Inhibition of p38a MAPK (unknown origin) by radiometric assay				Bioorg Med Chem Lett 24: 1352-7 (2014) Article DOI: 10.1016/j.bmcl.2014.01.034 BindingDB Entry DOI: 10.7270/Q2D221KT
					More data for this Ligand-Target Pair