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SMILES: OC[C@H]1OC(O)[C@@H]([C@@H](O)[C@@H]1O)n1cc(nn1)-c1nc(c(o1)-c1ccncc1)-c1ccc(F)cc1

InChI Key: InChIKey=HVUYOKFQUXOKMH-DVKCISKWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496074   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))		BDBM50496074
PNG
(CHEMBL3121005)
Show SMILES OC[C@H]1OC(O)[C@@H]([C@@H](O)[C@@H]1O)n1cc(nn1)-c1nc(c(o1)-c1ccncc1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C22H20FN5O6/c23-13-3-1-11(2-4-13)16-20(12-5-7-24-8-6-12)34-21(25-16)14-9-28(27-26-14)17-19(31)18(30)15(10-29)33-22(17)32/h1-9,15,17-19,22,29-32H,10H2/t15-,17-,18-,19-,22?/m1/s1
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PC cid
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PubMed
n/an/a 1.19E+3n/an/an/an/an/an/a



Syncom B.V.

Curated by ChEMBL


Assay Description
Inhibition of p38a MAPK (unknown origin) by radiometric assay

Bioorg Med Chem Lett 24: 1352-7 (2014)


Article DOI: 10.1016/j.bmcl.2014.01.034
BindingDB Entry DOI: 10.7270/Q2D221KT
More data for this
Ligand-Target Pair