BDBM50496334 CHEMBL3126189

SMILES: OC(C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1cc(F)cc(F)c1

InChI Key: InChIKey=OAOHJPWUVQFOCX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Menin (Homo sapiens (Human))	BDBM50496334 (CHEMBL3126189) Show SMILES OC(C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1cc(F)cc(F)c1 Show InChI InChI=1S/C27H32F2N2O2/c28-24-16-23(17-25(29)18-24)27(32,21-4-1-2-5-21)22-10-13-31(14-11-22)12-3-15-33-26-8-6-20(19-30)7-9-26/h6-9,16-18,21-22,32H,1-5,10-15H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	436	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Inhibition of human His-tagged menin-biotinylated MLL (4 to 15) interaction after 1 hr by HTRF assay				J Med Chem 57: 1543-56 (2014) Article DOI: 10.1021/jm401868d BindingDB Entry DOI: 10.7270/Q2XS5ZCB
					More data for this Ligand-Target Pair