BDBM50496405 CHEMBL3127403

SMILES: Clc1ccccc1CN(C[C@@H]1CCC(=O)N1)S(=O)(=O)c1cccc(c1)C#N

InChI Key: InChIKey=KLNILPUJBKLJSM-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50496405 (CHEMBL3127403) Show SMILES Clc1ccccc1CN(C[C@@H]1CCC(=O)N1)S(=O)(=O)c1cccc(c1)C#N |r| Show InChI InChI=1S/C19H18ClN3O3S/c20-18-7-2-1-5-15(18)12-23(13-16-8-9-19(24)22-16)27(25,26)17-6-3-4-14(10-17)11-21/h1-7,10,16H,8-9,12-13H2,(H,22,24)/t16-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 ion channel expressed in CHO cells by patch clamp assay				Bioorg Med Chem Lett 24: 1269-73 (2014) Article DOI: 10.1016/j.bmcl.2014.01.067 BindingDB Entry DOI: 10.7270/Q2930X4D
					More data for this Ligand-Target Pair