BDBM50496410 CHEMBL3127399

SMILES: CCN1[C@H](CN(Cc2ccc(F)cc2)S(=O)(=O)c2cccc(c2)C#N)CCC1=O

InChI Key: InChIKey=ZKFMDZYNXFFEJW-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50496410   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-gated potassium channel (Homo sapiens (Human))	BDBM50496410 (CHEMBL3127399) Show SMILES CCN1[C@H](CN(Cc2ccc(F)cc2)S(=O)(=O)c2cccc(c2)C#N)CCC1=O |r| Show InChI InChI=1S/C21H22FN3O3S/c1-2-25-19(10-11-21(25)26)15-24(14-16-6-8-18(22)9-7-16)29(27,28)20-5-3-4-17(12-20)13-23/h3-9,12,19H,2,10-11,14-15H2,1H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 ion channel expressed in CHO cells by patch clamp assay				Bioorg Med Chem Lett 24: 1269-73 (2014) Article DOI: 10.1016/j.bmcl.2014.01.067 BindingDB Entry DOI: 10.7270/Q2930X4D
					More data for this Ligand-Target Pair