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SMILES: COc1cccc(\C=C2\N(CC(C)C)C(=O)C(Br)=C2c2cc(Cl)ccc2OC)c1

InChI Key: InChIKey=WLYOUDNRUOSMRK-YBFXNURJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497195   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cholesterol side-chain cleavage enzyme, mitochondrial


(Rattus norvegicus)		BDBM50497195
PNG
(CHEMBL3116169)
Show SMILES COc1cccc(\C=C2\N(CC(C)C)C(=O)C(Br)=C2c2cc(Cl)ccc2OC)c1 |c:17|
Show InChI InChI=1S/C23H23BrClNO3/c1-14(2)13-26-19(11-15-6-5-7-17(10-15)28-3)21(22(24)23(26)27)18-12-16(25)8-9-20(18)29-4/h5-12,14H,13H2,1-4H3/b19-11+
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.92E+3n/an/an/an/an/an/a



Federal University of Vi£osa

Curated by ChEMBL


Assay Description
Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysis

Eur J Med Chem 82: 127-38 (2014)


Article DOI: 10.1016/j.ejmech.2014.05.035
BindingDB Entry DOI: 10.7270/Q29K4F6V
More data for this
Ligand-Target Pair