BindingDB logo
myBDB logout

null

SMILES: Oc1cnccc1CCCOc1cccnc1Oc1cccc(Cl)c1

InChI Key: InChIKey=HBUJRYNMNPGQOW-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497250   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50497250
PNG
(CHEMBL3299084)
Show SMILES Oc1cnccc1CCCOc1cccnc1Oc1cccc(Cl)c1
Show InChI InChI=1S/C19H17ClN2O3/c20-15-5-1-6-16(12-15)25-19-18(7-2-9-22-19)24-11-3-4-14-8-10-21-13-17(14)23/h1-2,5-10,12-13,23H,3-4,11H2
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 33n/an/an/an/an/an/a



Dainippon Sumitomo Pharma Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibition of human PDE4

Bioorg Med Chem Lett 24: 2689-92 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.052
BindingDB Entry DOI: 10.7270/Q2XD14P4
More data for this
Ligand-Target Pair