null

SMILES: OC(=O)CCCCC(=O)Nc1ccc(cc1)-c1nc2cc(Cl)ccc2[nH]1

InChI Key: InChIKey=WVNRWRZRXZCXMT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit B (Staphylococcus aureus)	BDBM50497515 (CHEMBL3344018) Show SMILES OC(=O)CCCCC(=O)Nc1ccc(cc1)-c1nc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C19H18ClN3O3/c20-13-7-10-15-16(11-13)23-19(22-15)12-5-8-14(9-6-12)21-17(24)3-1-2-4-18(25)26/h5-11H,1-4H2,(H,21,24)(H,22,23)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science-Pilani Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase B ATPase activity				Bioorg Med Chem 22: 5970-87 (2014) Article DOI: 10.1016/j.bmc.2014.09.008 BindingDB Entry DOI: 10.7270/Q23X89MP
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50497515 (CHEMBL3344018) Show SMILES OC(=O)CCCCC(=O)Nc1ccc(cc1)-c1nc2cc(Cl)ccc2[nH]1 Show InChI InChI=1S/C19H18ClN3O3/c20-13-7-10-15-16(11-13)23-19(22-15)12-5-8-14(9-6-12)21-17(24)3-1-2-4-18(25)26/h5-11H,1-4H2,(H,21,24)(H,22,23)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology & Science-Pilani Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus DNA gyrase-mediated supercoiling of relaxed DNA using pBR 322 as substrate by agarose gel electrophoresis analysi...				Bioorg Med Chem 22: 5970-87 (2014) Article DOI: 10.1016/j.bmc.2014.09.008 BindingDB Entry DOI: 10.7270/Q23X89MP
					More data for this Ligand-Target Pair