BDBM50497776 CHEMBL3310311
SMILES: Cc1nc2ccccn2c1C(=O)N\N=C\c1ccc(C)cc1
InChI Key: InChIKey=BVPFUKZKGPSCKH-WOJGMQOQSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pantothenate synthetase (Mycobacterium tuberculosis (strain ATCC 25618 / H3...) | BDBM50497776![]() (CHEMBL3310311) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Birla Institute of Technology & Science-Pilani Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis pantothenate synthetase expressed in Escherichia coli BL21 (DE3) by spectrophotometry | Bioorg Med Chem 22: 4223-32 (2014) Article DOI: 10.1016/j.bmc.2014.05.038 BindingDB Entry DOI: 10.7270/Q2D79FDX | |||||||||||
More data for this Ligand-Target Pair |