BDBM50497933 CHEMBL3341995

SMILES: Cc1oc2nc(nn2c1CNCCc1ccccc1Cl)-c1ccccc1Cl

InChI Key: InChIKey=DKPZZVPIYQJWID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497933   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50497933 (CHEMBL3341995) Show SMILES Cc1oc2nc(nn2c1CNCCc1ccccc1Cl)-c1ccccc1Cl Show InChI InChI=1S/C20H18Cl2N4O/c1-13-18(12-23-11-10-14-6-2-4-8-16(14)21)26-20(27-13)24-19(25-26)15-7-3-5-9-17(15)22/h2-9,23H,10-12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR method				Bioorg Med Chem Lett 24: 3690-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.038 BindingDB Entry DOI: 10.7270/Q2KS6VJM
					More data for this Ligand-Target Pair