BDBM50498228 CHEMBL3577758

SMILES: Cc1nccc2c3ccc(OCc4ccc(Cl)cc4)cc3n(Cc3ccc(Cl)cc3)c12

InChI Key: InChIKey=TXTYPHUZJRRWDS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chitinase (Onchocerca volvulus)	BDBM50498228 (CHEMBL3577758) Show SMILES Cc1nccc2c3ccc(OCc4ccc(Cl)cc4)cc3n(Cc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C26H20Cl2N2O/c1-17-26-24(12-13-29-17)23-11-10-22(31-16-19-4-8-21(28)9-5-19)14-25(23)30(26)15-18-2-6-20(27)7-3-18/h2-14H,15-16H2,1H3	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assessed as releas...				ACS Med Chem Lett 6: 339-43 (2015) Article DOI: 10.1021/ml500516r BindingDB Entry DOI: 10.7270/Q2C53PTX
					More data for this Ligand-Target Pair