BDBM50498655 CHEMBL1895209

SMILES: COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCN(C)CC1

InChI Key: InChIKey=LDFAJFPHFKEJOI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50498655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone-lysine N-methyltransferase EHMT1/EHMT2 (Homo sapiens (Human))	BDBM50498655 (CHEMBL1895209) Show SMILES COc1cc2nc(nc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC)N1CCN(C)CC1 Show InChI InChI=1S/C27H36N6O2/c1-31-13-15-33(16-14-31)27-29-23-18-25(35-3)24(34-2)17-22(23)26(30-27)28-21-9-11-32(12-10-21)19-20-7-5-4-6-8-20/h4-8,17-18,21H,9-16,19H2,1-3H3,(H,28,29,30)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
Imperial College London Curated by ChEMBL					Assay Description Inhibition of G9a (unknown origin) using [histone H3 1 to 25 residues] and SAM substrate by scintillation proximity assay				Medchemcomm 5: 1821-1828 (2014) Article DOI: 10.1039/c4md00274a BindingDB Entry DOI: 10.7270/Q2V127VK
					More data for this Ligand-Target Pair