BDBM50499451 CHEMBL3741199

SMILES: CC(C)c1nc(-c2nnc(o2)C2CCN(CC2)C2CCC2)c2ccccn12

InChI Key: InChIKey=ZFXPLSPARWTGJB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50499451   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50499451 (CHEMBL3741199) Show SMILES CC(C)c1nc(-c2nnc(o2)C2CCN(CC2)C2CCC2)c2ccccn12 Show InChI InChI=1S/C21H27N5O/c1-14(2)19-22-18(17-8-3-4-11-26(17)19)21-24-23-20(27-21)15-9-12-25(13-10-15)16-6-5-7-16/h3-4,8,11,14-16H,5-7,9-10,12-13H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	840	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd. Curated by ChEMBL					Assay Description Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay				Eur J Med Chem 103: 289-301 (2015) Article DOI: 10.1016/j.ejmech.2015.08.051 BindingDB Entry DOI: 10.7270/Q20C4ZST
					More data for this Ligand-Target Pair