null

SMILES: COc1ccc(cc1)C1=Cc2ccc(F)cc2C(CC(=O)CO)N1c1ccc(O)cc1

InChI Key: InChIKey=OWQHPMJECIZGDO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50499583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrase (Human immunodeficiency virus 1)	BDBM50499583 (CHEMBL3741049) Show SMILES COc1ccc(cc1)C1=Cc2ccc(F)cc2C(CC(=O)CO)N1c1ccc(O)cc1 |t:9| Show InChI InChI=1S/C25H22FNO4/c1-31-22-10-3-16(4-11-22)24-12-17-2-5-18(26)13-23(17)25(14-21(30)15-28)27(24)19-6-8-20(29)9-7-19/h2-13,25,28-29H,14-15H2,1H3	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase strand transfer activity preincubated for 30 mins followed by addition of FITC-labelled dsDNA for 1 hr by microplate re...				ACS Med Chem Lett 6: 1065-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00230 BindingDB Entry DOI: 10.7270/Q2348PDM
					More data for this Ligand-Target Pair
Integrase (Human immunodeficiency virus 1)	BDBM50499583 (CHEMBL3741049) Show SMILES COc1ccc(cc1)C1=Cc2ccc(F)cc2C(CC(=O)CO)N1c1ccc(O)cc1 |t:9| Show InChI InChI=1S/C25H22FNO4/c1-31-22-10-3-16(4-11-22)24-12-17-2-5-18(26)13-23(17)25(14-21(30)15-28)27(24)19-6-8-20(29)9-7-19/h2-13,25,28-29H,14-15H2,1H3	PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Delhi Curated by ChEMBL					Assay Description Inhibition of HIV-1 integrase G140S mutant strand transfer activity preincubated for 30 mins followed by addition of FITC-labelled dsDNA for 1 hr by ...				ACS Med Chem Lett 6: 1065-70 (2015) Article DOI: 10.1021/acsmedchemlett.5b00230 BindingDB Entry DOI: 10.7270/Q2348PDM
					More data for this Ligand-Target Pair