BDBM50500094 CHEMBL3740203

SMILES: OC(=O)c1ccc(NC(c2ccc(Br)cc2)c2ccc3cccnc3c2O)cc1

InChI Key: InChIKey=PKCXEKWXPIBUME-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500094   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prenyl protein specific protease (Homo sapiens (Human))	BDBM50500094 (CHEMBL3740203) Show SMILES OC(=O)c1ccc(NC(c2ccc(Br)cc2)c2ccc3cccnc3c2O)cc1 Show InChI InChI=1S/C23H17BrN2O3/c24-17-8-3-15(4-9-17)20(26-18-10-5-16(6-11-18)23(28)29)19-12-7-14-2-1-13-25-21(14)22(19)27/h1-13,20,26-27H,(H,28,29)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
New York University Abu Dhabi Curated by ChEMBL					Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...				Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ
					More data for this Ligand-Target Pair