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BDBM50500095 CHEMBL2003928

SMILES: Cc1ccc(NC(c2ccccc2)c2ccc3cccnc3c2O)cc1

InChI Key: InChIKey=HUMXPASVXGPBQJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500095   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
CAAX prenyl protease 2


(Homo sapiens (Human))		BDBM50500095
PNG
(CHEMBL2003928)
Show SMILES Cc1ccc(NC(c2ccccc2)c2ccc3cccnc3c2O)cc1
Show InChI InChI=1S/C23H20N2O/c1-16-9-12-19(13-10-16)25-21(17-6-3-2-4-7-17)20-14-11-18-8-5-15-24-22(18)23(20)26/h2-15,21,25-26H,1H3
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.80E+3n/an/an/an/an/an/a



New York University Abu Dhabi

Curated by ChEMBL


Assay Description
Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...

Bioorg Med Chem 24: 160-78 (2016)


Article DOI: 10.1016/j.bmc.2015.11.043
BindingDB Entry DOI: 10.7270/Q2NS0XXQ
More data for this
Ligand-Target Pair