BDBM50500096 CHEMBL3739720

SMILES: OC(=O)c1ccc(NC(c2cccnc2)c2ccc3cccnc3c2O)cc1

InChI Key: InChIKey=GBMKAWBYRBHVGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prenyl protein specific protease (Homo sapiens (Human))	BDBM50500096 (CHEMBL3739720) Show SMILES OC(=O)c1ccc(NC(c2cccnc2)c2ccc3cccnc3c2O)cc1 Show InChI InChI=1S/C22H17N3O3/c26-21-18(10-7-14-3-2-12-24-20(14)21)19(16-4-1-11-23-13-16)25-17-8-5-15(6-9-17)22(27)28/h1-13,19,25-26H,(H,27,28)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
New York University Abu Dhabi Curated by ChEMBL					Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...				Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ
					More data for this Ligand-Target Pair