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BDBM50500102 CHEMBL3740606

SMILES: Oc1c(ccc2ccccc12)C(Nc1ccccc1)c1c(F)cc(Br)cc1F

InChI Key: InChIKey=IZLZMEQLFUZWSE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500102   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prenyl protein specific protease


(Homo sapiens (Human))		BDBM50500102
PNG
(CHEMBL3740606)
Show SMILES Oc1c(ccc2ccccc12)C(Nc1ccccc1)c1c(F)cc(Br)cc1F
Show InChI InChI=1S/C23H16BrF2NO/c24-15-12-19(25)21(20(26)13-15)22(27-16-7-2-1-3-8-16)18-11-10-14-6-4-5-9-17(14)23(18)28/h1-13,22,27-28H
KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.40E+3n/an/an/an/an/an/a



New York University Abu Dhabi

Curated by ChEMBL


Assay Description
Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...

Bioorg Med Chem 24: 160-78 (2016)


Article DOI: 10.1016/j.bmc.2015.11.043
BindingDB Entry DOI: 10.7270/Q2NS0XXQ
More data for this
Ligand-Target Pair